Abstract
Three new prenylated flavanones, (2S)-5,7,2'-trihydroxy-5'-(1''',1'''-dimethylallyl)-8-prenylflavanone (1), (2S)-5,7,2'-trihydroxy-8,3'-diprenylflavanone (2), and (2S)-5,2'-dihydroxy-6'',6''-dimethylchromeno-(7,8:2'',3'')-3'-prenylflavanone (3), and a known chromeno (dimethylpyrano) flavanone, obovatin (4), were isolated from the n-hexane extract of Dalea boliviana roots. The compounds were evaluated in vitro in relation to their inhibitory effect on the tyrosinase activity by using a spectrophotometric method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Argentina
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Fabaceae / chemistry*
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Flavanones / chemistry
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Flavanones / isolation & purification*
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Flavanones / pharmacology*
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Inhibitory Concentration 50
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Molecular Structure
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Monophenol Monooxygenase / antagonists & inhibitors*
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Stereoisomerism
Substances
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(2S)-5,7,2'-trihydroxy-5'-(1''',1'''-dimethylallyl)-8-prenylflavanone
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5,2'-dihydroxy-6'',6''-dimethylchromeno-(7,8:2'',3'')-3'-prenylflavanone
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5,7,2'-trihydroxy-8,3'-diprenylflavanone
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Flavanones
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Monophenol Monooxygenase